2 edition of Selected abstracts on postoperative adjuvant therapy of breast cancer found in the catalog.
Selected abstracts on postoperative adjuvant therapy of breast cancer
Gabriel N. Hortobagyi
by U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, U.S. Dept. of Commerce, National Technical Information Service [distributor in [Bethesda, Md.], Springfield, Va
Written in English
|Statement||Gabriel N. Hortobagyi, consulting reviewer.|
|Contributions||International Cancer Research Data Bank.|
|The Physical Object|
|Pagination||vii, 54 p. ;|
|Number of Pages||54|
In , ASCO published an adaptation of the Cancer Care Ontario guideline on the selection of optimal adjuvant chemotherapy regimens for early breast cancer and adjuvant targeted therapy for human epidermal growth factor receptor 2 (HER2)–positive breast cancers. 1 ASCO updates its guidelines at intervals determined by an Update Steering Group of the original Expert Panel. Background We compared the efficacy of two different taxanes, docetaxel and paclitaxel, given either weekly or every 3 weeks, in the adjuvant treatment of breast cancer. Methods We enrolled wo.
Surgical, cosmetic, quality of life, and life expectancy must be taken into account when selecting the way to integrate breast reconstruction and PMRT. Cancer Control. Jan-Dec ;25(1) doi: / A widely accepted evidence-based treatment approach used in patients with early HER2-positive breast cancer is surgery, followed by adjuvant therapy, for patients with clinical stage T1N0 disease.
Ahead of the ASCO Virtual Scientific Program, we spoke with a handful of leading oncologists in breast cancer, lung cancer, gastrointestinal cancers, genitourinary cancers, and . Daniel Becker, Dawn L. Hershman, in Management of Cancer in the Older Patient, Adjuvant Therapies: Radiotherapy. Adjuvant radiotherapy may be used in two settings: after breast-conserving therapy and after mastectomy. A review of alm women age 65 or older treated for breast cancer in the s found that approximately 76% of the patients who had lumpectomies also had .
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Get this from a library. Selected abstracts on postoperative adjuvant therapy of breast cancer. [Gabriel N Hortobagyi; International Cancer Research Data Bank.]. Objective: To provide health care providers, patients, and the general public with a current consensus on various issues related to the use of adjuvant therapy for breast cancer.
Participants: A nonfederal, nonadvocate, member panel representing the fields of oncology, radiology, surgery, pathology, statistics, public health, health policy, and the public; 30 experts in medical oncology.
In addition, the favorable effect of adjuvant treatments on long-term survival and recurrence has been well acknowledged in non-small cell lung cancer, gastric cancer, breast cancer, colon cancer, and ampulla of Vater cancer [7–11].
Currently, surgical resection is still the main treatment for the patients with by: 7. Abstract. A prospective randomised multicentre clinical study was undertaken for 2 years and 3 months from Novemberwith the aim of examining the significance of using a combination of ftorafur (FT) and tamoxifen (TAM) for post-operative adjuvant therapy of breast cancer.
Maria Clara Rodriguez Palleiro, Gabriel Krygier Waltier, The impact of 21‐Gene Recurrence Score test and classic clinical‐pathologic factors in guiding adjuvant therapy for HER‐2 negative, ER‐positive, early‐stage breast cancer: A retrospective study, The Breast Journal, /tbj, 26, 5, Cited by: 8.
As this review focuses on decision‐making in the immediate postoperative adjuvant setting, we have not included an evaluation of gene expression assays in the setting of neoadjuvant or extended adjuvant therapy, even when the LOE was high (e.g., Sgroi et al.
Excluded also were publications not relating to female invasive breast cancer and. Importance: Radiotherapy (RT) after breast-conserving surgery for early-stage disease has become an integral part of breast cancer treatment.
This article reviews the rationale and indications for adjuvant radiotherapy to the breast and regional lymph nodes. Observations: Randomized trials have demonstrated a significant benefit in tumor control in the treated breast following whole-breast RT.
Subsequently, CIK cell-based therapy has been broadly adopted as an adjuvant treatment combined with chemotherapy for treating multiple types of cancers, such as renal cell carcinoma 9, gastric can non-small cell lung can colon can and liver can with great efficacy and safety.
Breast Cancer in the Elderly. Breast cancer death rates in both United States and European populations have declined during the past decade. However, there is a preferential improvement observed in younger women of less than 75 years [3,4] despite the generally favorable tumor biology in the older population .This is most likely related to underuse of standard adjuvant treatments (either.
Morimoto T, Ogawa M, Orita K, et al. Postoperative adjuvant randomised trial comparing chemoendocrine therapy, chemotherapy and immunotherapy for patients with stage II breast cancer.
There is growing evidence that intraoperative radiation therapy (IORT) may be a viable option in selected patients with early breast cancer. This study reports our 4‐year experience with IORT. The perioperative outcome and imaging data of all patients who underwent IORT for early breast cancer at a tertiary medical center in ‐ were.
Decisions regarding postoperative adjuvant treatment for rectal cancer are based primarily on tumor location, clinical stage, histologic stage, and history of neoadjuvant therapy. Proximal rectal/rectosigmoid tumors are located at least 12 cm proximal to the anal verge and are above the peritoneal reflection.
Background: The relative value of trastuzumab (H) monotherapy as an adjuvant treatment compared to the standard combination treatment with chemotherapy (CT) is not clear for elderly breast cancer (BC) patients (pts). Methods: We randomly assigned pts over 70 years (yrs) old with HER2-positive invasive BC who received curative surgery into either H (H group) or H plus CT.
INTRODUCTION. The outcomes of patients with early breast cancer have been improved with the use of adjuvant systemic treatments 1, which include chemotherapy, endocrine therapy, and targeted agents (trastuzumab) for eligible subgroups of l clinical practice guidelines make recommendations for the selection of adjuvant systemic therapy based on primary evidence or.
Breast carcinoma is the second most frequent cause of cancer‐related death for women in the U.S. 1 In the firstline treatment of patients affected by metastatic breast carcinoma (MBC), polychemotherapy produces advantages in terms of response rate and median time to disease progression (TTP) over single‐agent chemotherapy.
2 Anthracyclines (doxorubicin and epirubicin) are. Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer: an overview of 61 randomized trials am women. N Engl J Med ; - Full Text. Objective: This study aimed to evaluate the cost-effectiveness of postoperative adjuvant tamoxifen therapy using data from a Korean breast cancer registry.
Methods: In this retrospective, observational cohort study, patients were selected from the Korean Breast Cancer Society database. Women with stage I, II, or III breast cancer (diagnosed between and ), for whom information about.
Since standard adjuvant therapy for HER2-positive breast cancer is 1 year of HER2-targeted therapy, completion of this therapy in patients undergoing neoadjuvant therapy has become an. Background: The optimal sequence of mastectomy with immediate breast reconstruction (IBR) and radiotherapy (RT) for the treatment of locally advanced breast cancer (LABC) is still under debate.
Increased rates of postoperative complications are described following postmastectomy RT. Neoadjuvant RT aims to improve the aesthetic results and simplify the reconstructive pathway.
Introduction. Although surgery is still an indispensable therapy for current treatment of solid tumors, neoadjuvant combination therapy and postoperative adjuvant combination therapy play an increasingly important role in the clinical outcomes of patients. 1 Tumor recurrence and wound infection are two major challenges after surgery.
2 To obtain maximized therapeutic benefits, the. Abstract. The use of neoadjuvant chemotherapy has become more prevalent in the treatment of breast cancer patients. The finding of a pathologic complete response to neoadjuvant chemotherapy (no evidence of residual invasive cancer in the breast and lymph nodes at the time of surgical resection) has been shown to correlate with improved survival.Abstract.
Background: A multi-institutional randomized clinical trial of adjuvant therapy for patients with high-risk node-negative (n0) breast cancer has been undertaken in Japan. The pathology panel was organized in order to establish histological criteria to identify patient groups with.
Breast cancer is still the leading malignant tumor for women [1,2,3,4,5,6].In the last few years, the treatment is improving due to new surgical techniques, new systemic therapeutic options and a better understanding of the biology of the disease [7,8,9].Furthermore, there are also advances in the field of radiation oncology [10, 11] (Fig.
1).This review will report about the recent advances.